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Year : 2016  |  Volume : 3  |  Issue : 1  |  Page : 49-51

Palmar pigmentation: An unusual presentation of alkaptonuria

Department of Dermatology, Venereology and Leprosy, Narayana Medical College, Nellore, Andhra Pradesh, India

Correspondence Address:
Dr. H. V. S. Naveen Kumar
Flat No: 201, H. No: 1-1-524, R. R. Arcade, Gandhinagar, Hyderabad, Telangana - 500 080
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/2349-5847.184245

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Alkaptonuria (AKU) is a rare inherited autosomal recessive metabolic disorder, caused by the deficiency of homogentisic acid oxidase enzyme. Herein, we are reporting a case of AKU with bilaterally symmetrical palmar pigmentation and skeletal involvement. Histopathological examination revealed ochre colored pigment in the dermis whereas roentgenogram of the lumbar spine showed typical calcification of the intervertebral discs.

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