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CASE REPORT
Year : 2022  |  Volume : 9  |  Issue : 1  |  Page : 51-54

Vitiligo: an uncommon cutaneous manifestation of graft versus host disease


Department of Dermatology, Armed Forces Medical College, Pune, India

Correspondence Address:
Dr. Preema Sinha
Department of Dermatology, Armed Forces Medical College, Pune 411040
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/Pigmentinternational.Pigmentinternational_

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Graft versus host disease (GVHD) is the most serious complication of hematopoietic stem cell transplantation. Skin is the most commonly affected organ, in both acute and chronic GVHD with a variable clinical spectrum of presentation with the typical skin lesions being either lichenoid or sclerodermatous. Antibodies developing in chronic GVHD act as triggering factors in the development of autoimmune diseases and can manifest as vitiligo that is an autoimmune disease resulting in melanocyte destruction. Vitiligo as sequelae and manifestation of GVHD is infrequently reported in the literature. Herein, we report the case of a lady who developed vitiligo post hematopoietic stem cell transplant.


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