Pigment International

ORIGINAL ARTICLE
Year
: 2021  |  Volume : 8  |  Issue : 3  |  Page : 153--158

Cross-sectional pilot study of clinical and histopathological features of periorbital dark circles in South Asians


Tara Rao1, Allison L Wang2, Ildiko Polyak3, Jag Bhawan3, Amit G Pandya1 
1 Department of Dermatology, University of Texas Southwestern Medical Center, Dallas, Texas, USA
2 Divison of Dermatology, Cook County Health and Hospital Systems, Chicago, Illinois, USA
3 Department of Dermatology, Boston University School of Medicine, Boston, Massachusetts, USA

Correspondence Address:
Allison L Wang
Divison of Dermatology, Cook County Health and Hospital Systems, 1950 W. Polk St. Chicago IL 60612
USA

Background: Periorbital dark circles are common in all races. Proposed causes include increased vasculature, tear-trough deformity, pigmentary demarcation lines, spongiotic dermatitis, lichenoid dermatitis, acanthosis nigricans, post-inflammatory hyperpigmentation, and heredity. Aims: To evaluate the clinical features and histopathological features of dark circles compared to nearby unaffected skin in South Asians. Methods: Clinical evaluation, skin biopsies, and narrow-band reflectance spectrophotometry of periorbital dark circles and nearby unaffected skin were performed on all subjects. Results: There was a positive correlation between the clinical severity of dark circles and increased melanin based on spectrophotometry. Histological evaluation showed increased dermal melanin content in dark circles compared to normal skin. Limitations: Single-center pilot study. Conclusion: Dark circles in this cohort of South Asians are associated with increased dermal melanin. Other contributing factors may include exaggerated tear trough depression, translucency of eyelid skin, and pigmentary demarcation lines.


How to cite this article:
Rao T, Wang AL, Polyak I, Bhawan J, Pandya AG. Cross-sectional pilot study of clinical and histopathological features of periorbital dark circles in South Asians.Pigment Int 2021;8:153-158


How to cite this URL:
Rao T, Wang AL, Polyak I, Bhawan J, Pandya AG. Cross-sectional pilot study of clinical and histopathological features of periorbital dark circles in South Asians. Pigment Int [serial online] 2021 [cited 2021 Dec 4 ];8:153-158
Available from: https://www.pigmentinternational.com/article.asp?issn=2349-5847;year=2021;volume=8;issue=3;spage=153;epage=158;aulast=Rao;type=0